Synergistic antimicrobial action of antibiotics and plant extracts on pathogens

Abstract

Plants such as Neem, Clove, Cinnamon, Aloe vera, Ginger are used as medicinal plants since long time. They produce secondary metabolites such as alkaloids glycoside etc, which are responsible for the antimicrobial activity of the plants. The ethanolic extracts of these plants produce lysosome which is capable of killing pathogens. The antimicrobial activity of these plant extracts is checked on pathogens such as E. coli, S. aureus, P. aeruiginosa. Agar well diffusion technique was used for checking the antimicrobial activity of plants extract with synergy of antibiotics penicillin, ampicillin and streptomycin. 90µl of extract was mixed with 10 µl of antibiotic solution and the plates were observed for inhibition zone. The most inhibition zone was observed for Aloe vera, Clove and Neem and least was observed for Cinnamon and Ginger.