To evaluate the pharmacological activity of Nymphaea alba using in-vitro anthelmintic model

Abstract

This research explored the anthelmintic potential of an ethanolic extract derived from Nymphaea alba flowers against earthworms, roundworms, and tapeworms. The outcomes indicate a concentration-dependent anthelmintic effect of the extract. Introduction: Nymphaea alba, commonly referred to as the white-water lily, has a rich history of medicinal utilization across various traditional healing systems. This study aimed to scrutinize the potential anthelmintic properties of its flowers. Materials and Methods: The ethanolic extract of Nymphaea alba flowers was meticulously prepared. Anthelmintic activity was evaluated using earthworms, roundworms, and tapeworms sourced from pigs. Various concentrations (25, 50, and 100 mg/ml) of the extract were tested, and the paralysis and death times of the worms were meticulously recorded. Results: The extract demonstrated concentration-dependent anthelmintic activity against all three worm species. Higher concentrations led to accelerated paralysis and death times. Albendazole and piperazine citrate served as positive controls, exhibiting a more robust anthelmintic effect compared to the extract. Conclusion: The findings suggest that the ethanolic extract of Nymphaea alba flowers holds promise as an anthelmintic agent. However, further investigation is warranted to elucidate the specific active constituents and their efficacy in vivo models.