Ethnobotanical study and anthelmintic investigation of Detarium microcarpum (Fabaceae)

Abstract

African flora in general, and Nigerian flora in particular, is rich in medicinal plants. The aim of this study is to contribute to a better understanding of Detarium microcarpum and its evaluation in terms of the anthelmintic activity of its organs. Ethnobotanical surveys were carried out using questionnaires with herbalists and traditional practitioners, and extracts of the various organs were evaluated in vitro for their anthelmintic activity. The results enabled us to list the medicinal uses of D. microcarpum, particularly for gastrointestinal diseases. Extracts of trunk bark, roots and leaves showed a positive effect on earthworms during the trial (1.50 mg/mL < LD50 < 2.70 mg/mL). The results obtained may justify the traditional use of Detarium microcarpum in the treatment of certain diseases of parasitic origin.