Comparative effects of fresh palm oil and vitamin E on lipid profile in thermo-oxidized palm oil fed albino rat

Abstract

The human population consuming thermally-oxidized palm oil (TPO) is on the increase and there is no known remedy to it associated diseases. This study evaluates the impacts of fresh palm oil and vitamin E on lipid profiles of rat fed TPO. Sixty albino male rats were grouped into 6 (n=10). Group 2, 3, 4, 5 and 6 were fed TPO, fresh palm oil, vitamin E, TPO + fresh palm oil and TPO + vitamin E respectively. Group 1 acted as the control. 15 g of the oils was added to 85 g rat food to prepare respective diet and vitamin E 200 mg/kg/day orally. After treatment, serum analysis revealed that TPO significantly (p<0.05) alter lipid profiles negatively compared to control. But fresh palm oil and vitamin E significantly (p<0.05) reverses lipid profiles of TPO fed rats. Fresh palm oil and vitamin E may boost lipid indices and lessen the chance of cardiovascular harms.