Sequence identification of toll like receptor 6 in dromedary camel (Camelus dromedarius)

Abstract

The present study was conducted for the mRNA sequence identification of Toll-like receptor 6 (TLR 6) gene of Camelus dromedarius. It was made up of 2496 nucleotide-long open reading frame (ORF) and the encoded protein was 831 amino acid-long. The sequence was submitted to the NCBI with accession no. MN807291. TLR 6 gene was found to be located on chromosome 2. It consists of total three exon in which second and third exons were involved in expression of gene. The 3D structure of the gene revealed a curved or horseshoe-shape. The amino acid (aa) sequence had four leucine-rich repeat (LRR) domains followed by one C – terminal LRR domain, a transmembrane membrane domain, and an intracellular Toll–interleukin (IL)-1 receptor (TIR) domain.