Hematological effects of Azadirachta indica (Neem) extract on New Zealand white male rabbits: A comprehensive study

Abstract

Neem (Azadirachta indica) is a versatile tree native to India, with bioactive compounds in its seed, leaf, flower, bark, and roots, offering a wide range of applications. While concerns about neem causing sterility in some bird species have been raised, this study investigates its impact on hematological parameters in New Zealand White male rabbits. The rabbits were divided into control and two treatment groups, receiving varying doses of neem extract. Haematological parameters, including hemoglobin, packed cell volume, total leukocyte count, granulocyte count, lymphocyte count, eosinophil count, total erythrocyte count, and monocyte count, were measured at different time intervals. Results indicated that neem extract did not significantly alter these parameters, suggesting a non-toxic effect. The study provides valuable insights into the hematological impact of neem in rabbits, contributing to our understanding of its safety and potential applications.