In vitro anti-oxidant and anti-diabetic activity of Brucine and Eugenol in combination

Abstract

The present study evaluates the In vitro anti-oxidant and In vitro anti-diabetic activity of Brucine and eugenol in combination in various models. The anti-oxidant activity by hydrogen peroxide method was performed it has IC50 value of 39.52 µg/ml. The Ferrous reducing activity of Brucine and eugenol in combination has IC50 value 16.33 µg/ml. The phytochemical in combination has shown α-Amylase inhibitory activity and has IC50 value of 55.83 µg/ml. The In vitro studies clearly indicate that Brucine and eugenol in combination has synergic effect against oxidation reaction and in the treatment of diabetes when compared to individual therapy with Brucine and eugenol alone.