Anti-inflammatory and anti-aging potential of extracts and constituents from Teucrium lucidum L. aerial parts

Abstract

The property of hydroalcoholic extract of aerial part of Teucrium lucidum L. and some constituents were evaluated as antioxidant and as inhibitors of enzymes involved in inflammation using in vitro bioassays. Bioguided fractionation led to the characterization of 8 compounds, including 5 unknown ones in the Teucrium genus, and to their structural elucidation (NMR and HRMS experiments). Among them, 5,3’,5’-trihydroxyflavone-7-O-β-xylosyl-(1’’’→6’’)-β-glucopyranoside is reported here for the first time. With the help of GC-MS analysis, 23 volatile compounds were identified and quantified in the T. lucidum extract, and a total of 38 compounds were finally identified through this study.