Pharmacognostic evaluation and fingerprint profile of raw materials and formulation of Sufoof-e-bars: A remedy for vitiligo

Abstract

Vitiligo is one of the commonest skin disorders characterized by the appearance of completely de-pigmented milky white macules of varying sizes and shapes which certainly inflicts tremendous psycho-sociological stress on patients. Sufoof-e-Bars is a traditional Unani formulation widely used for clinical treatment of Vitiligo. The present investigation was therefore undertaken to determine the requisite pharmacognostic standards, phytochemical analysis, fluorescence analysis, heavy metal detection and HPTLC fingerprint profile of raw materials and Sufoof-e-Bars. The results obtained for physico-chemical constants were within the acceptable pharmacopeial limits. The preliminary phytochemical analysis of raw materials showed the presence of Alkaloids, Glycosides, Steroids, Tannins etc. The HPTLC fingerprint profile developed for the separation of phytoconstituents is unique to raw materials and formulation of Sufoof-e-Bars. Thus, the scientifically generated data from the current studies will help to overcome batch to batch variation and will also project this formulation in global market in a proper prospective.