Study of 1,4 Dihydropyridine derivative for Antifungal Activity

Abstract

1,4 Dihydropyridines are very versatile compounds and have very important role as therapeutic agents. The 1, 4 Dihydropyridines (1,4 DHPs) are well known as calcium channel blocker and their use in treatment of cardiovascular diseases is very common. These compounds are also known to have antimicrobial activities. These N-heterocyclic compounds represent very important framework for agricultural and pharmaceutical industries. These are also known to have antibacterial and antifungal activities. Hence, the substituted 1, 4- Dihydropyridine derivate was synthesized in presence of tetra butyl ammonium bromide catalyst and evaluated for its antifungal activity. The results showed the compound was effective.