Quality evaluation of Rauvolfia serpentina by physicochemical analysis

Abstract

Objective: Rauvolfia serpentina plant species is used since ancient time. Now days it has been became endangered plant species in India due to climacteric changes and increased demand in drug industry. Hence comparative physiochemical analysis of wild and cultivated species is necessary. Rauvolfia serpentina mother tincture is having specific target action on hypertension. Thus before initiating phytochemical standardization and in vivo study, validation of manufacturing process and physicochemical analysis is essential. Methods: According to HPI guidelines, two samples of Rauvolfia serpentina mother tincture were prepared from wild and cultivated species in GMP certified homoeopathic manufacturing unit. Further validation and comparative physicochemical analysis were done for both samples. Results: The physicochemical parameters of Rauvolfia serpentina mother tincture prepared from wild and cultivated species were almost alike. Conclusion: This analytical data will be possibly considered as quality standard for Rauvolfia serpentina mother tincture prepared from wild and cultivated species in further research. The process of manufacturing and physicochemical values of wild and cultivated samples are validated and established in the study.