Osteitis and cerebral empyema in sickle cell disease: About two cases

Abstract

Subdural empyema or brain abscess are infectious lesions which can complicated meningitis or frontal sinusitis infection. Spontaneous cranial vault osteomyelitis or osteitis followed by cerebral empyema are rare intracranial complications which can occured in sickle cell disease and immune compromise due to intravenous drug abuse. Sickle cell disease is a hemoglobinopathy responsible for many complications that are sometimes severe. Importance or early diagnosis and proper treatment is the key for the managment for these complications. The authors reported two cases of subdural empyema which were surgically evacuated and treated with adapted antibiotics with good outcomes.