Ultrasound elastography and MR elastography for assessing liver fibrosis

Abstract

Background: Liver fibrosis is a common result of many chronic liver diseases and if progressive leads to cirrhosis. The present study was conducted to compare the ultrasound elastography and MR Elastography for assessing liver fibrosis.Material and Methods: The present study 50 patients with diagnosed liver fibrosis were included in the study. The clinically obtained biopsy specimen was reviewed by single person and scored the histologic features using the NASH Clinical Research Network histologic scoring system. The pathologist was blinded to imaging data. Sonographers were blinded to clinical, histological, and MRI data. MR analysts were blinded to clinical, histological, and ultrasound data. The Statistical difference was assessed and statistical significance was assessed at a type I error rate of 0.05.Results: In the present study on histopathogical examination it was found that in total, 45, 37, 4, 19, and 5 had fibrosis stages 0, 1, 2, 3, and 4, respectively. The Accuracy of MRE was significantly higher than those of SWE for diagnosing any fibrosis. Conclusion: The present study concluded that MR Elastography was better than ultrasound elastography for assessing liver fibrosis.