Hematological & biochemical parameters of dengue and its prevalence in North India: A hospital based study

Abstract

Introduction: We undertook this prospective study to assess the clinical profile of dengue infection in hospitalized patients as well as to observe rare manifestations of dengue fever in the current outbreak.Materials and Methods: Blood samples collected in vaccutainers for Hb, Haematocrit, Platelets, leukocyte count, AST, ALT & dengue viral specific antigen (NS1) &IgM, IgG antibody. Hb, Haematocrit, platelets count, leukocytes count done manually method/automated hematological- analyzer & AST, ALT values determined by the automated biochemistry - Analyzer.Result: All the patients show body rash, vomiting, abdominal pain, back pain &spleenomegaly. In hematological finding, the average of haemoglobin 13.0 gm/dl, haematocrit 38.29%, total leukocyte count 6.3 Lac. Cells per cubic mm, thrombocyte count 2.12 lacks where mild decreases of platelet count. In biochemical finding, moderate decrease AST (191.33IU/L) & ALT(232.25IU/L)valuein dengue patient's serum.Conclusion: The destruction of mosquito is necessary, which transmitted dengue virus.