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Prognostic and Diagnostic role of HE4 as a biomarker in ovarian cancer & comparison with CA125 in ovarian cancer patients with their menopausal status
International Journal of Advanced Biochemistry Research · 2022 · Vol. 6(2) · pp. 52–56
Geeta Bilonia✉(Sawai ManSingh Medical College and Hospital)Rati Mathur(Solid Material Solutions (United States))Suresh Singh(Solid Material Solutions (United States))
Abstract
Aim: to evaluate a new tumour marker HE4, in comparison with CA 125 and the Risk of Ovarian cancer in pre and postmenopausal women with ovarian cancer.Method: The ovarian cancer female patients were recruited from OPD/IPD of Surgery and Oncology department of SMS Hospital, and evaluated serum human epididymis protein (HE4) and CA125 Patients were divided into two group’s premenopausal and postmenopausal women with ovarian cancer.Results: Serum HE4 and CA125 level significantly high in postmenopausal women as compared to premenopausal women of ovarian cancer. The result was significantly high. (p
Ovarian cancer diagnosis and treatmentOvarian cancerMedicineBiomarkerPostmenopausal womenOncologyCancerInternal medicineEpididymisMenopauseGynecology
Citations
0
FWCI
0.00
field-weighted impact
References
19
Percentile
15%
vs. same field & year
References
A novel multiple marker bioassay utilizing HE4 and CA125 for the prediction of ovarian cancer in patients with a pelvic mass
Gynecologic Oncology · 2008 · 855 citations
A Major Human Epididymis-Specific cDNA Encodes a Protein with Sequence Homology to Extracellular Proteinase Inhibitors1
Biology of Reproduction · 1991 · 392 citations
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