Spectacular efficacy of isotretinoin in pustular psoriasis in a child

Abstract

Generalized pustular psoriasis (GPP) occurs rarely in children, it is a chronic inflammatory disorder characterized by the presence of aseptic pustules overlying on erythematous plaques with systemic symptoms such as fever and fatigue. We report the case of a GPP treated with isotretinoin with success. Our case emphasizes that isotretinoin can be considered as a good option in the treatment of pediatric psoriasis because of its short half-life but its effectiveness has not been yet established.