Gram-negative antimicrobial spectrum of Ulmus pumila

Abstract

Antibiotic resistance by gram-negative bacteria is becoming a major global health crisis. The objective of this study is to examine the antibacterial activity of Ulmus pumila against a variety of infectious gram-negative bacteria. The extraction of Ulmus pumila leaves and flowers were carried out using 95% ethanol. The homogenate was filtered and sterile paper discs were soaked in the filtrate. Discs infused with extracts or only 95% ethanol, were placed on bacterial plates and incubated. Antibacterial activity was tracked by measuring the zones of inhibition. In this research, Ulmus pumila displayed antibacterial activity against P. vulgaris, E. coli, K. pneumoniae, and E. cloacae. With the results of this experiment and the previous activity of Ulmus pumila against gram-positive bacteria, there is much potential for Ulmus pumila to be developed into a broad-spectrum antibacterial agent.