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Effect of polyherbal formulation for immunomodulation in immunosuppressed mice
International Journal of Pharmacognosy and Life Science · 2022 · Vol. 3(1) · pp. 19–23
Pratibha Sonawane✉(Tatyasaheb Kore Dental College and Research Centre)M Rasiklal(Tatyasaheb Kore Dental College and Research Centre)Jitendra Kandale(Tatyasaheb Kore Dental College and Research Centre)Santosh Bhujbal(Tatyasaheb Kore Dental College and Research Centre)
Abstract
A Polyherbal Formulation is prepared by using Methanolic extract of Sphaeranthus indicus flowerheads, fruits of Piper nigrum, Hydroalcoholic extracts of Withania somnifera, Ocimum sanctum, Centella asiatica for immunomodulatory activity. The effects of 100mg, 200mg, 400mg were screened on humoral and cellular immunity i.e. HA titer and Delayed Type Hypersensitivity on immunosuppressed mice. The present study demonstrated that the formulation200mg, 400mg have synergistic immunostimulant activity in HA titer and DTH, and it also showed protection against cyclophosphamide induced immunoosupression.
Phytochemicals and Medicinal PlantsMedicinal Plants and NeuroprotectionDiverse Scientific Research StudiesTraditional medicineWithania somniferaOcimumImmunostimulantCentellaTiterBiologyMedicineImmunologyImmune system
Citations
1
FWCI
0.31
field-weighted impact
References
9
Percentile
64%
vs. same field & year
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