Isolation of alkaloids Chabamide I, Piperine and Chingchengenamide: A from Piper chaba H. Leaves and their in vitro antimicrobial activities

Abstract

A known alkaloids Chabamide I, Piperine and new alkaloids Chingchengenamide A were isolated from the methanol extract of dichloromethane fraction of Piper chaba leaves. The chemical structure of these compounds were established by detailed spectral data and in comparison with their spectral data reported earlier. The study was also performed to determine the in vitro antimicrobial activity by disc diffusion method. Among them, the pure compound 1 showed good antimicrobial activity against all of the test micro-organisms, fungi and standard Kanamycin.