Phenolic glycosides from roots of Clerodendrum myricoides

Abstract

Clerodendrum myricoides is a plant traditionally used for treatment of rheumatism, asthma, inflammatory diseases, coughs, skin diseases, vermifuge, febrifuge and malaria. Phytochemical screening of the CH2Cl2/CH3OH (1:1) and CH3OH (100%) root extracts of the plant revealed the presence of phenolic compounds, steroids, flavonoids, saponins and terpenes. Chromatographic separation of CH2Cl2/CH3OH (1:1) root extract of C. myricoides yielded a new phenylpropanoid glycoside (1) together with a known phenylpropanoid glycoside, verbascoside-6III-apiose (2). The structures of these compounds were determined using spectroscopic techniques (UV-Vis, IR and NMR, 1D and 2D).