Cardiac changes in patients of chronic kidney disease

Abstract

Uremic Cardiomyopathy thought to be the pathological cardiac hypertrophy, indicating the influence of impaired renal function on the myocardium. It is the result of pressure overload, volume overload, and the uremic state itself. LV pressure overload occurs frequently from hypertension and arteriosclerosis, and occasionally from aortic stenosis; LV volume overload occurs as a result of the presence of an arteriovenous fistula, anemia, and hypervolemia. Cardiovascular complications are a major cause of morbidity and mortality in CKD patients, accounting for approximately 50% of deaths. Written informed consent was obtained from the all the subjects included in the study. In the present study, 36 cases presented with systolic dysfunction. Among them 6% cases had mild systolic dysfunction, 18% had moderate systolic dysfunction and 12% had severe systolic dysfunction. In the present study 09 cases presented with diastolic dysfunction and 05 cases constituted grade 1 diastolic dysfunction, 04 cases constituted grade II diastolic dysfunction.