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Synthesis, characterization and antimicrobial screening of N-(3-amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-5-yl)-2-chloro-substitutedquinoline-3-carboxamides

International Journal of Chemical Studies · 2021 · Vol. 9(2) · pp. 694–699
Preeti RajputAbhilekha Sharma

Abstract

A sequence of N-(3-amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-5-yl)-2-chloro-substitutedquinoline-3-carboxamides (6a-n) compounds synthesized and characterized by various analytical techniques. Synthesized compounds were screened for their antibacterial and antifungal activity against different strains and gives moderate to excellent activities. After performing statistical analysis, present research showed significant co-relation of the synthesized compounds.

Synthesis and Characterization of Heterocyclic CompoundsSynthesis and biological activitySynthesis and Biological EvaluationAntifungalAntimicrobialAntibacterial activityChemistryCombinatorial chemistrySequence (biology)StereochemistryOrganic chemistryMicrobiologyBacteria
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References
Quinolines as potent 5-lipoxygenase inhibitors: Synthesis and biological profile of L-746,530
Bioorganic & Medicinal Chemistry Letters · 1998 · 271 citations
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Synthesis, characterization and antimicrobial screening of N-(3-amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-5-yl)-2-chloro-substitutedquinoline-3-carboxamides · Scinovex