Antimicrobial and antioxidant properties of Coriandrum sativum L. seed essential oil

Abstract

In the present study the essential oil of Coriandrum sativum L. seed was extracted by hydrodistillation and investigated for the antimicrobial activity against clinical pathogens E. coli, Enteobacter aerogenes, Klebsiella, P. aeruginosa and C. albicans by microdilution method, Minimum bactericidal concentration and antioxidant activity by DPPH assay. Results showed that MIC was minimum 0.02mg/ml and 0.04mg/ml for C. albicans and Klebsiella pneumoniae and maximum 1.28 mg/ml for P. aeruginosa, followed by E. coli 0.64 mg/ml. The minimum bactericidal concentration results showed that the MBC value ranges from 0.02mg/ml to 2.56mg/ml. The MBC and or MFC value is low for C. albicans 0.04mg/ml and high for P. aeruginosa 2.56mg/ml. The essential oil of Coriandrum sativum L. seed showed significant antioxidant activity and the percentage of inhibition were 66.2% and 87.8% for standard ascorbic acid. The IC50 value were 0.147 mg/ml and 0.108 mg/ml.