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First-line nivolumab plus ipilimumab combined with two cycles of chemotherapy in patients with non-small-cell lung cancer (CheckMate 9LA): an international, randomised, open-label, phase 3 trial

The Lancet Oncology · 2021 · Vol. 22(2) · pp. 198–211
Luis Paz‐AresTudor–Eliade CiuleanuManuel CoboMichael SchenkerBogdan ŻurawskiJ. MenezesEduardo RichardetJaafar BennounaEnriqueta FelipÓscar JuanAurelia AlexandruHiroshi SakaiAlejo LinguaPamela SalmanPierre-Jean SouquetPedro De MarchiClaudio MartínM. PérolArnaud ScherpereelShun LüThomas JohnDavid P. CarboneS. Meadows–ShropshireShruti AgrawalAbderrahim OukessouJinchun YanMartin Reck
Cancer Immunotherapy and BiomarkersLung Cancer Treatments and MutationsLung Cancer Diagnosis and TreatmentIpilimumabNivolumabMedicineClinical endpointInternal medicineLung cancerChemotherapyInterim analysisPhases of clinical researchOncology

MeSH terms

IpilimumabNivolumabAgedAntineoplastic Combined Chemotherapy ProtocolsCarcinoma, Non-Small-Cell LungFemaleHumansMaleMiddle AgedNeoplasm Recurrence, LocalNeoplasm StagingTreatment OutcomeDisease-Free Survival

Funding

  • Bristol-Myers Squibb
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First-line nivolumab plus ipilimumab combined with two cycles of chemotherapy in patients with non-small-cell lung cancer (CheckMate 9LA): an international, randomised, open-label, phase 3 trial · Scinovex