Efficacy of Toxicodendron pubescens in relation with serum hyaluronic acid and its application on primary osteoarthritis

Abstract

Toxicodendron Pubescens (Rhus Tox), a Homeopathic medicine frequently used for Osteoarthritis is evaluated with the help of Serum Hyaluronic acid level. A total of 44 patients with knee Primary Osteoarthritis (OA) were taken into the study for the follow-up period up to 3 months and Serum Hyaluronic Acid is measured through Eliza test before and after administering Rhus Tox200 three time a day. Homoeopathy implies a particular way of applying drugs to diseases according to a specific Principle: known as ‘Similia similibus curentur’. This implies that substances capable of causing disorder in healthy subjects are used as medicines to treat similar patterns of disorder experienced by ill people. According to aphorism 248 the dose of the same medicine may be repeated several times according to the circumstances, but only so long as until either recovery ensures, or the same remedy ceases to do good and the rest of the disease presenting a different group of symptoms demands a different homoeopathic remedy. Analyzed the symptoms according to the Knee injury and Osteoarthritis Outcome Score (KOOS), which was developed as an extension of the WOMAC Osteoarthritis Index with the purpose of evaluating short-term and long-term symptoms and function in subjects with knee injury and osteoarthritis. The KOOS holds five separately scored subscales: Pain, other Symptoms, Function in daily living (ADL), Function in Sport and Recreation (Sport/Rec), and knee-related Quality of Life (QOL). A significant alteration in Serum Hyaluronic Acid is noted in patients suffering from Primary Osteoarthritis is marked with significant P value.