Effect of aqueous extract of Anagallis arvensis and its amelioration by Tribulus terrestris in Wistar rats: Haemato biochemical study

Abstract

The subacute toxicopathological study was conducted to note toxic effect of Anagallis arvensis and its amelioration by Tribulus terrestris treatment in Wistar rats. The study was conducted for 28 days and evaluated through haemato biochemical changes at 0, 14th and 28th day of trial. The toxicated rats showed significant reduction in Hb, PCV, TEC at 14th as well as 28th day and Neutrophil at 28th only whereas, there was significant increase mean value of TLC, and blood clotting time at 14th and 28th day and Lymphocyte at 28th day only. There was significant incline in AST, BUN Creatinine and Phosphorus level with decline in total protein and calcium level in toxicated rats. The mean ALT and blood glucose levels were numerically increased than control group in toxicated rats. The mean values of haematological and biochemical parameters in rats of treatment group remained comparable with control group indicating its beneficial effect.