GC-MS analysis, antibacterial, antioxidant and brine shrimp lethality assay of Zanthoxylum armatum DC.
Abstract
Fruit part of Zanthoxylum armatum DC. was subjected to extraction of essential oil by hydro distillation in Clevenger apparatus. Dried and powdered plant was subjected to extraction with methanol. The composition of essential oil so collected were determined by GC-MS system and showed the presence of 20 different compounds. The most abundant were β-Linalool (60.00%), Methyl cinnamate (16.28%) and 3-Carene (9.69%). Antibacterial and antioxidant activity of the essential oil of Z. armatum were studied. Oil exhibited moderate antibacterial activity. Z. armatum showed efficient DPPH antioxidant activity with IC50 58.5± 4.2μg/mL. The LD50 of the sample was found to be 35.1μg/mL in Brine shrimp lethality assay.
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