Study of spectrum of neoplastic and non-neoplastic lesions in fallopian tube in a tertiary care hospital

Abstract

Background: Fallopian tubes are affected by a wide spectrum of diseases varying from salpingitis to carcinoma. Most pathological processes involving the fallopian tube are inflammatory and are of clinical significance because they interfere with the function of the fallopian tube and result in infertility. Although fallopian tube is affected by a wide spectrum of diseases, a literature search reveals that there are only occasional studies, documenting histologic changes in the fallopian tube removed for all reasons. This prompts the present study. The aim is to study the gross and microscopic features of the excised fallopian tubes and to study the common and unusual lesions in them and to study the frequency of histological findings and relative frequencies of different findings. Materials and methods: Four hundred and forty-five cases of fallopian tubes that were removed were studied retrospectively, and their histopathological findings documented. Results: The majority of the fallopian tubes had inflammatory changes comprised of acute and chronic salpingitis, salpingitis isthmica nodosa, tuberculous salpingitis, xanthogranulomatous salpingitis, hematosalpinx, and hydrosalpinx. Sixteen cases comprised of ectopic pregnancy. One case of primary fallopian tube adenocarcinoma and two cases of metastatic adenocarcinoma. Conclusion: The majority of the fallopian tubes remain unremarkable in a majority of the surgical pathology specimens, yet the fallopian tube must be subjected to a thorough histopathological examination to evaluate the various pathological lesions.