Determination and comparison of antimicrobial activity of Psidium guajava and Emblica officinalis against MDR bacteria

Abstract

The antimicrobial activities of Psidium guajava (guava) and Emblica officinalis (amla) were determined and compared against 2 gram +ve (Staphylococcus aureus and Bacillus cereus) and 2 gram -ve bacteria (Salmonella typhi and Escherichia coli), which are Multi Drug Resistant (MDR). The guava and amla leaves were crushed and their extract was taken in methanol and ethanol respectively. The efficiency of these extracts were tested against MDR bacteria through well diffusion assay. In this study both extract showed inhibitory activity against MDR bacteria. The methanol extract of guava showed maximum antimicrobial activity against B. cereus (gram +ve) followed by S. aureus (gram +ve) while lesser inhibition against S. typhi (gram -ve) and least inhibition against E. coli (gram -ve) was observed. The ethanol extract of amla showed maximum inhibition against Salmonella typhi (gram -ve) while minimum against Staphylococcus aureus (gram +ve). On the basis of present findings it was concluded that both the extracts possesses antimicrobial and pharmacological properties, hence can be used parallel to synthetic drugs which have undesirable side effects.