Susceptibility of antibiotic resistant bacteria to plant extract (Psidium guajava)

Abstract

Background and objectives: Methicillin Resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa represent a worldwide threat because of their virulence, drug resistance and nosocomial infection. Bioactive compounds from traditional medicinal plants show promising role in treatment to control bacterial infections. We aimed to report the anti-bacterial activity of methanolic leaf extract of Psidium guajava. Materials and Methods: The prospective study includes 50 MRSA and 17 Drug resistant Pseudomonas aeruginosa. Methanolic leaf extract was done by using soxhlet apparatus. These isolates were subjected to perform antimicrobial susceptibility testing by Well- diffusion method.Results: Out of 50 MRSA, 45 are sensitive. Out of 17 Pseudomonas aeruginosa, 8 are sensitive to methanolic leaf extract.Interpretation and conclusion: We need of alternative drugs to treat resistance organisms. Methanolic leaf extract of Psidium guajava has some antibacterial property.