Preliminary phytochemical screening and in vitro antacid activity of Hemidesmus indicus leaves extract by modified artificial stomach model

Abstract

Hemidesmus indicus (Asclepiadaceae) is important medicinal plants in traditional Indian medicine. The present study was designed to investigate the phytochemical constituents, fluorescence nature and antacid activity of Hemidesmus indicus leaves by using a modified artificial stomach model. Parameters such as effect of temperature on pH, neutralization effect, duration of neutralization effect and capacity were evaluated. Sodium bicarbonate and water were used as reference and control respectively. Hemidesmus indicus leaves containing phytochemical constituents such as Tannins, Saponins, Terpenoids, Alkaloids, and phenolic compounds, Steroids, Glycosides, Triterpenoids and Flavonoids etc. Fluorescence analysis signifies their characteristics. Hemidesmus indicus leaves produced relatively good responses on effect of temperature on pH, neutralization effect, duration of neutralization effect and capacity. It was found to be higher than that of water but less when compared to sodium bicarbonate. Hence this plant can be an effective alternative for sodium bicarbonate which is reported to have various side effects.