Antimicrobial activity of Tectona grandis against MDR enteric pathogens

Abstract

India is a rich source of medicinal plants and plant kingdom is valuable source of many new medicines which act as a natural remedies for certain diseases. In this study, an attempt had made to find out the antimicrobial activity of Tectona grandis leaves (pure and hybrid variety) against enteric bacterial pathogens. Plant extract was prepared using Chloroform and suspended in DMSO solution. Comparative study of leaf extract (Pure and hybrid) were evaluated by disc diffusion method against different pathogenic bacteria viz. Staphylococcus aureus, Bacillus cereus, Salmonella typhi and Escherichia coli. The result obtained revealed that plant showed maximum inhibition against gram positive bacteria rather than gram negative bacteria. Comparatively it was also observed that hybrid variety of Tectona grandis showed more antimicrobial activity than the pure variety. This study concludes that the phytochemicals obtained from Tectona grandis can be used in several gastrointestinal ailment and can be commercialised.