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Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis

BMJ · 2020 · Vol. 370 · pp. m3320–m3320

John Allotey✉(University of Birmingham)Silvia Fernández-García(Instituto Ramón y Cajal de Investigación Sanitaria)Mercedes Bonet(World Health Organization)Elena Stallings(Instituto Ramón y Cajal de Investigación Sanitaria)Magnus Yap(University of Birmingham)Tania Kew(University of Birmingham)Dengyi Zhou(University of Birmingham)Dyuti Coomar(University of Birmingham)Jameela Sheikh(University of Birmingham)Heidi Lawson(University of Birmingham)Kehkashan Ansari(University of Birmingham)Shruti Attarde(University of Birmingham)Megan Littmoden(University of Birmingham)Adeolu Banjoko(University of Birmingham)Kathryn Hughes Barry(University of Birmingham)Oluwadamilola Akande(University of Birmingham)Dharshini Sambamoorthi(University of Birmingham)Madelon van WelyElisabeth van Leeuwen(University of Amsterdam)Elena KostovaHeinke Kunst(Queen Mary University of London)Asma Khalil(St George's, University of London)Simon Tiberi(Queen Mary University of London)Vanessa Brizuela(World Health Organization)Nathalie Broutet(World Health Organization)Edna Kara(World Health Organization)Caron Rahn Kim(World Health Organization)Anna Thorson(World Health Organization)Ramón EscurietSami L. Gottlieb(World Health Organization)Van T. Tong(CDC Foundation)Sascha Ellington(CDC Foundation)Olufemi T. Oladapo(World Health Organization)Lynne Mofenson(Elizabeth Glaser Pediatric AIDS Foundation)Javier Zamora(Queen Mary University of London)Shakila Thangaratinam(Birmingham Women’s and Children’s NHS Foundation Trust)

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Abstract

This article is a living systematic review that will be updated to reflect emerging evidence. Updates may occur for up to two years from the date of original publication. This version is update 1 of the original article published on 1 September 2020 (BMJ 2020;370:m3320), and previous updates can be found as data supplements (https://www.bmj.com/content/370/bmj.m3320/related#datasupp). When citing this paper please consider adding the update number and date of access for clarity.

COVID-19 Impact on Reproduction Maternal Mental Health During Pregnancy and Postpartum Pregnancy and preeclampsia studiesMedicineOdds ratioConfidence intervalPregnancyMeta-analysisObstetricsmyalgiaCochrane LibraryCohort studyMEDLINE

MeSH terms

BetacoronavirusCOVID-19SARS-CoV-2FemaleHumansInfant, NewbornPneumonia, ViralPregnancyPregnancy Complications, InfectiousPrognosisRisk FactorsGlobal HealthIntensive Care, NeonatalCoronavirus InfectionsPremature Birth