A clinicopathological study of Xanthogranulomatous pyelonephritis

Abstract

Introduction: Rare, severe and atypical form of chronic pyelonephritis characterized by destruction of renal parenchyma and the presence of granulomas, abscesses, and collection of lipid filled macrophages. Objective: To study the clinicopathological relationship of the lesion. Method: A 8 year retrospective study was done to analyze the lesions of renal and ureteric calculi. XGP was found to be most common in female. Conclusion: Xanthogranulomatous pyelonephritis is unusual variant of chronic pyelonephritis. Preoperative diagnosis is desirable with laboratory analysis. Histopathological examination is important to know the type and etiological factor of the lesion.