Successful therapeutic management of Acetaminophen toxicity in a kitten

Abstract

A five months old male kitten weighing about 1.3 kg was presented with the history of weakness, anorexia, vomiting and diarrhoea after administration of 250 mg acetaminophen tablet for fever. The kitten was in sternal recumbency and depressed mental state. Normal temperature (38.3º C), tachycardia (96/min), dyspnoea, brown colour mucous membrane and facial oedema (Fig 1) were observed. Haematobichemical examination revealed moderate anaemia and elevated blood urea nitrogen, creatinine, total billirubin, alanine aminotransferase and alkaline phosphatase. The kitten was treated with N-acetylcystine (NAC), ringers lactate, ascorbic acid, ranitidine and S-adenosyl methionine (SAMe). It showed uneventful recovery on fifth day.