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Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants

Nature Reviews Microbiology · 2019 · Vol. 18(2) · pp. 67–83

Kira S. Makarova✉(National Center for Biotechnology Information)Yuri I. Wolf(National Center for Biotechnology Information)Jaime Iranzo(National Center for Biotechnology Information)Sergey Shmakov(National Center for Biotechnology Information)Omer S. Alkhnbashi(TU Bergakademie Freiberg)Stan J. J. Brouns(Delft University of Technology)Emmanuelle Charpentier(Max Planck Unit for the Science of Pathogens)David R. ChengDaniel H. Haft(National Center for Biotechnology Information)Philippe Horvath(DuPont (France))Sylvain Moineau(Université Laval)Francisco J. M. Mojica(University of Alicante)David ScottShiraz A. Shah(University of Copenhagen)Virginijus Šikšnys(Vilnius University)Michael P. Terns(University of Georgia)Česlovas Venclovas(Vilnius University)Malcolm F. White(University of St Andrews)Alexander F. Yakunin(Bangor University)Winston X. YanFeng Zhang(Broad Institute)Roger A. Garrett(University of Copenhagen)Rolf Backofen(University of Freiburg)John van der Oost(Wageningen University & Research)Rodolphe Barrangou(North Carolina State University)Eugene V. Koonin(National Center for Biotechnology Information)

CRISPR and Genetic Engineering Evolution and Genetic DynamicsBiologyCRISPRClass (philosophy)Computational biologyGeneticsEvolutionary biologyGeneComputer scienceArtificial intelligence