Antioxidant, antibacterial and antiacetylcholinesterase activities of Phalaris canariensis from Tunisia

Abstract

This study evaluates the antioxidant, antibacterial and antiacetylcholinesterase activities as well as phenolic contents of various extracts from Phalaris canariensis. The results showed that the methanol extract is endowed with the highest antiacetylcholinesterase activity (PI = 65.0%) and the best radical scavenging property with IC50=0.12 mg/mL. Meanwhile, this extract was found to have the highest phenolic content (190.58 mg gallic acid equivalents/g extract). Moreover, the ethyl acetate extract exhibited the best reducing power effect and the highest total antioxidant capacity (330.9 mg vitamin E/mg extract). In addition, the best antibacterial effect was observed for the methanolic extract against Micrococcus luteus. It was noticed that the extents of antiacetylcholinesterase, antibacterial and antioxidant activities of Phalaris canariensis extracts are in accordance with their phenolic compounds.