Phytochemical and biological investigation of the leaves of Ravenea rivularis (Arecaceae)

Abstract

The main objective of this work is isolation and characterization of chemical compounds with biological studies from the leaves of Ravenea rivularis (Arecaceae). Materials and Methods: The air dried plants extracted with70% methanol, n-hexane, ethyl acetate and n-butanol. The compounds were isolated by column chromatography, TLC, PTLC and paper chromatography. The isolated compounds were identified by spectroscopic methods as 1H NMR, UV and MS. Results: The compounds identified are Lupeol acetate, Betulinic acid, Apigenin, Luteolin, luteolin-7-O-I²-D-glucopyranoside, ferulic acid, caffeic acid and chlorogenic acid. The leave extracts from Ravenea rivularis exhibited antioxidant activity, anti-inflammatory and cytotoxicity against Hep-G2. All those compounds are been reported for the first time in Ravenea rivularis.