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Integrated analysis of lncRNA-miRNA-mRNA ceRNA network in squamous cell carcinoma of tongue

BMC Cancer · 2019 · Vol. 19(1) · pp. 779–779

Rui-Sheng Zhou✉(First Affiliated Hospital of Guangzhou University of Chinese Medicine)Enxin Zhang(First Affiliated Hospital of Guangzhou University of Chinese Medicine)Qinfeng Sun(Shandong University)Zengjie Ye(Guangzhou University of Chinese Medicine)Jianwei Liu(Jinan Stomatological Hospital)Dai-Han Zhou(First Affiliated Hospital of Guangzhou University of Chinese Medicine)Ying Tang(Guangzhou University of Chinese Medicine)

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Abstract

In this study, we described the gene regulation by the lncRNA-miRNA-mRNA ceRNA network in the progression of SCCT. We propose a new lncRNA-associated ceRNA that could help in the diagnosis and treatment of SCCT.

Cancer-related molecular mechanisms research MicroRNA in disease regulation RNA modifications and cancerCompeting endogenous RNAmicroRNABiologyComputational biologyMessenger RNAKEGGGeneLong non-coding RNABioinformaticsGenetics

MeSH terms

AgedAged, 80 and overCarcinoma, Squamous CellFemaleHumansMaleMiddle AgedNeoplasm StagingRNA, MessengerTongue NeoplasmsBiomarkers, TumorGene Expression Regulation, NeoplasticComputational BiologyGene Expression ProfilingMicroRNAs