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A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

Cell · 2011 · Vol. 146(3) · pp. 353–358
Leonardo SalmenaLaura PolisenoYvonne TayLev M. KatsPier Paolo Pandolfi
Cancer-related molecular mechanisms researchMicroRNA in disease regulationRNA modifications and cancerBiologyCompeting endogenous RNARNAComputational biologyGeneticsEvolutionary biologyGeneLong non-coding RNA

MeSH terms

AnimalsGene Expression RegulationHumansNeoplasmsPseudogenesRNARNA, MessengerGene Expression ProfilingRNA, UntranslatedMicroRNAs

Funding

  • American-Italian Cancer Foundation
  • Istituto Toscano Tumori
  • National Institutes of Health
  • Canadian Institutes of Health Research
  • National Health and Medical Research Council
Citations
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References
Most mammalian mRNAs are conserved targets of microRNAs
Genome Research · 2008 · 8,505 citations
The Genetic Signatures of Noncoding RNAs
PLoS Genetics · 2009 · 709 citations
A census of human cancer genes
Nature reviews. Cancer · 2004 · 3,334 citations
Regulation of mRNA Translation and Stability by microRNAs
Annual Review of Biochemistry · 2010 · 3,263 citations
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