Chemical composition, in vitro antioxidant, anti-inflammatory and antifeedant properties in the essential oil of Asian marsh weed Limnophila indica L. (Druce)

Abstract

Limnophila indica L. (Druce) is being estimated for the essential oil composition, in-vitro antioxidant, anti-inflammatory and insect antifeeding activity of this plant was evaluated. The GC-MS analysis led to identification of thirty-five compounds comprising of 90.9% of total oil composition. The major compound of the oil identified was epi-cyclocolorenone (27.7%). The oil was screened for antioxidant activity using reducing power assay, metal chelating of Fe+2 assay, NO and DPPH radical scavenging assay with IC50 21.19±0.06, 22.77±0.11, 15.74±0.06 and 14.52±0.05 µg/ml respectively. In-vitro anti-inflammatory activity assessment of the essential oil results in its activity with IC50 19.28±0.06 µg/ml. And also showed potent insect antifeeding action in a sequentially dose dependent manner against Spilosoma obliqua.