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Protecting-Group-Free Synthesis

Synthesis · 2006 · Vol. 2006(21) · pp. 3531–3541

Abstract

The introduction and removal of protecting groups are steps that unnecessarily increase the length of multistep syntheses. Hence, efficient syntheses are those that avoid the use of protecting groups. Protecting-group-free syntheses are highlighted in this review, in order to illustrate strategies by which the use of protecting groups can be minimized.

Synthetic Organic Chemistry Methods Chemical Synthesis and Reactions Chemical Synthesis and AnalysisProtecting groupChemistryGroup (periodic table)Combinatorial chemistryOrganic chemistry

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