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Continuous flow multi-step organic synthesis

Chemical Science · 2010 · Vol. 1(6) · pp. 675–675
Damien WebbTimothy F. Jamison

Abstract

Using continuous flow techniques for multi-step synthesis enables multiple reaction steps to be combined into a single continuous operation. In this mini-review we discuss the current state of the art in this field and highlight recent progress and current challenges facing this emerging area.

Innovative Microfluidic and Catalytic Techniques InnovationMicrofluidic and Capillary Electrophoresis ApplicationsChemical Synthesis and AnalysisContinuous flowCurrent (fluid)Computer scienceFlow (mathematics)Field (mathematics)Flow chemistryOrganic synthesisState (computer science)Process engineeringNanotechnology
Citations
674
FWCI
36.16
field-weighted impact
References
56
Percentile
100%
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Citations per year
References
Continuous Flow Reactors, a Tool for the Modern Synthetic Chemist
European Journal of Organic Chemistry · 2008 · 309 citations
Medicinal natural products: A biosynthetic approach
European Journal of Medicinal Chemistry · 2001 · 1,709 citations
Microchemical systems for continuous-flow synthesis
Lab on a Chip · 2009 · 496 citations
Continuous Flow Techniques in Organic Synthesis
Chemistry - A European Journal · 2003 · 466 citations
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Accounts of Chemical Research · 2002 · 2,170 citations
Flash Chemistry: Fast Chemical Synthesis by Using Microreactors
Chemistry - A European Journal · 2008 · 531 citations
Cascade Reactions in Total Synthesis
Angewandte Chemie International Edition · 2006 · 2,066 citations
Protecting-Group-Free Synthesis
Synthesis · 2006 · 281 citations
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