Scinovex
article Open AccessTop 1% cited

Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry

Nature Immunology · 2019 · Vol. 20(7) · pp. 928–942
Fan ZhangKevin WeiKamil SlowikowskiChamith Y. FonsekaDeepak A. RaoStephen KellySusan M. GoodmanDarren TabechianLaura B. HughesKaren Salomon-EscotoGerald F. WattsA. Helena JonssonJavier Rangel‐MorenoNida MeednuCristina RozoWilliam ApruzzeseThomas EisenhaureDavid LiebDavid L. BoyleArthur M. MandelinBrendan F. BoyceEdward F. DiCarloEllen M. GravallesePeter K. GregersenLarry W. MorelandGary S. FiresteinNir HacohenChad NusbaumEddie A. JamesHarris PerlmanCostantino PitzalisAndrew FilerV. Michael HolersVivian P. BykerkLaura T. DonlinJennifer H. AnolikMichael B. BrennerSoumya Raychaudhuri
T-cell and B-cell ImmunologySystemic Lupus Erythematosus ResearchCytokine Signaling Pathways and InteractionsRheumatoid arthritisMass cytometryFlow cytometryTranscriptomeInflammatory cellArthritisCellInflammationInflammatory arthritisImmunology

MeSH terms

Histocompatibility Antigens Class IIArthritis, RheumatoidCross-Sectional StudiesFibroblastsFlow CytometryHumansLeukocytesMonocytesSynovial MembraneSignal TransductionBiomarkersAutoimmunityGene ExpressionT-Lymphocyte SubsetsCytokines

Funding

  • Medical Research Council
Citations
1,345
FWCI
55.09
field-weighted impact
References
67
Percentile
100%
vs. same field & year
Citations per year
Cited by
References
Full-length RNA-seq from single cells using Smart-seq2
Nature Protocols · 2014 · 4,437 citations
Gene Ontology: tool for the unification of biology
Nature Genetics · 2000 · 43,975 citations
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
Proceedings of the National Academy of Sciences · 2005 · 55,472 citations
The mortality of rheumatoid arthritis
Arthritis & Rheumatism · 1994 · 1,323 citations
CEL-Seq2: sensitive highly-multiplexed single-cell RNA-Seq
Genome biology · 2016 · 1,231 citations
Single-cell RNA sequencing to explore immune cell heterogeneity
Nature reviews. Immunology · 2017 · 1,797 citations
Citation Network

How this paper connects to the literature. Drag to explore, click any node to open that paper.

Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry · Scinovex