article Open AccessTop 1% cited
Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry
Nature Immunology · 2019 · Vol. 20(7) · pp. 928–942
Fan Zhang✉(Broad Institute)Kevin Wei(Brigham and Women's Hospital)Kamil Slowikowski(Broad Institute)Chamith Y. Fonseka(Broad Institute)Deepak A. Rao(Brigham and Women's Hospital)Stephen Kelly(Barts Health NHS Trust)Susan M. Goodman(Hospital for Special Surgery)Darren Tabechian(University of Rochester Medical Center)Laura B. Hughes(University of Alabama at Birmingham)Karen Salomon-Escoto(University of Massachusetts Chan Medical School)Gerald F. Watts(Brigham and Women's Hospital)A. Helena Jonsson(Brigham and Women's Hospital)Javier Rangel‐Moreno(University of Rochester Medical Center)Nida Meednu(University of Rochester Medical Center)Cristina Rozo(Hospital for Special Surgery)William Apruzzese(Brigham and Women's Hospital)Thomas Eisenhaure(Broad Institute)David Lieb(Broad Institute)David L. Boyle(University of California San Diego)Arthur M. Mandelin(Northwestern University)Brendan F. Boyce(University of Rochester Medical Center)Edward F. DiCarlo(Hospital for Special Surgery)Ellen M. Gravallese(University of Massachusetts Chan Medical School)Peter K. Gregersen(Northwell Health)Larry W. Moreland(University of Pittsburgh)Gary S. Firestein(University of California San Diego)Nir Hacohen(Broad Institute)Chad Nusbaum(Broad Institute)Eddie A. James(Brigham and Women's Hospital)Harris Perlman(Northwestern University)Costantino Pitzalis(Queen Mary University of London)Andrew Filer(University Hospitals Birmingham NHS Foundation Trust)V. Michael Holers(University of Colorado Denver)Vivian P. Bykerk(Hospital for Special Surgery)Laura T. Donlin(Hospital for Special Surgery)Jennifer H. Anolik(University of Rochester Medical Center)Michael B. Brenner(Brigham and Women's Hospital)Soumya Raychaudhuri(Broad Institute)
T-cell and B-cell ImmunologySystemic Lupus Erythematosus ResearchCytokine Signaling Pathways and InteractionsRheumatoid arthritisMass cytometryFlow cytometryTranscriptomeInflammatory cellArthritisCellInflammationInflammatory arthritisImmunology
MeSH terms
Histocompatibility Antigens Class IIArthritis, RheumatoidCross-Sectional StudiesFibroblastsFlow CytometryHumansLeukocytesMonocytesSynovial MembraneSignal TransductionBiomarkersAutoimmunityGene ExpressionT-Lymphocyte SubsetsCytokines
Funding
- Medical Research Council
Citations
1,345
FWCI
55.09
field-weighted impact
References
67
Percentile
100%
vs. same field & year
Citations per year
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References
Full-length RNA-seq from single cells using Smart-seq2
Nature Protocols · 2014 · 4,437 citations
Gene Ontology: tool for the unification of biology
Nature Genetics · 2000 · 43,975 citations
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
Proceedings of the National Academy of Sciences · 2005 · 55,472 citations
The mortality of rheumatoid arthritis
Arthritis & Rheumatism · 1994 · 1,323 citations
CEL-Seq2: sensitive highly-multiplexed single-cell RNA-Seq
Genome biology · 2016 · 1,231 citations
Single-cell RNA sequencing to explore immune cell heterogeneity
Nature reviews. Immunology · 2017 · 1,797 citations
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