article Open AccessTop 1% cited
Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species
Immunity · 2019 · Vol. 50(5) · pp. 1317–1334.e10
Rapolas Žilionis(Center for Systems Biology)Camilla Engblom(Massachusetts General Hospital)Christina Pfirschke(Center for Systems Biology)Virginia Savova✉(Center for Systems Biology)David Zemmour(Harvard University)Hatice D. Saatcioglu(Harvard University)Indira Krishnan(Beth Israel Deaconess Medical Center)Giorgia Maroni(Institute of Biomedical Technologies)Claire V. Meyerovitz(Harvard University)Clara M. Kerwin(Harvard University)Sun Kil Choi(Harvard University)William G. Richards(Brigham and Women's Hospital)Assunta De Rienzo(Brigham and Women's Hospital)Daniel G. Tenen(Harvard University)Raphael Bueno(Harvard University)Elena Levantini(Beth Israel Deaconess Medical Center)Mikäel J. Pittet✉(Harvard University)Allon M. Klein✉(Center for Systems Biology)
Immune cells in cancerSingle-cell and spatial transcriptomicsEpigenetics and DNA MethylationBiologyMyeloidPopulationCellMyeloid cellsTranscriptomeImmunotherapyLung cancerSingle-cell analysisDendritic cell
MeSH terms
AnimalsBase SequenceCarcinoma, Non-Small-Cell LungDendritic CellsHumansLungLung NeoplasmsMacrophagesMaleMice, Inbred C57BLMonocytesNeutrophilsSequence Analysis, RNAGene Expression ProfilingCell Line, Tumor
Funding
- Deutsche Forschungsgemeinschaft
- Krebsliga Schweiz
- National University Cancer Institute, Singapore
- National Institutes of Health
Citations
1,454
FWCI
58.06
field-weighted impact
References
51
Percentile
100%
vs. same field & year
Citations per year
Cited by
Human Monocyte Subsets and Phenotypes in Major Chronic Inflammatory Diseases
Frontiers in Immunology · 2019 · 861 citations
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
Cancer Cell · 2023 · 3,276 citations
Macrophages as tools and targets in cancer therapy
Nature Reviews Drug Discovery · 2022 · 1,634 citations
Inflammation and Cancer: Triggers, Mechanisms, and Consequences
Immunity · 2019 · 3,596 citations
References
The prognostic landscape of genes and infiltrating immune cells across human cancers
Nature Medicine · 2015 · 3,213 citations
The Immunological Genome Project: networks of gene expression in immune cells
Nature Immunology · 2008 · 1,909 citations
Robust enumeration of cell subsets from tissue expression profiles
Nature Methods · 2015 · 13,801 citations
Monocytes and macrophages: developmental pathways and tissue homeostasis
Nature reviews. Immunology · 2014 · 1,786 citations
Online Survival Analysis Software to Assess the Prognostic Value of Biomarkers Using Transcriptomic Data in Non-Small-Cell Lung Cancer
PLoS ONE · 2013 · 1,850 citations
Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages
Nature Immunology · 2012 · 1,930 citations
Understanding the tumor immune microenvironment (TIME) for effective therapy
Nature Medicine · 2018 · 5,750 citations
Massively parallel digital transcriptional profiling of single cells
Nature Communications · 2017 · 7,553 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.