article Open AccessTop 1% cited
Robust enumeration of cell subsets from tissue expression profiles
Nature Methods · 2015 · Vol. 12(5) · pp. 453–457
Aaron M. Newman✉(California Institute for Regenerative Medicine)Chih Long Liu(California Institute for Regenerative Medicine)Michael R. Green(Stanford University)Andrew J. Gentles(Center for Systems Biology)Weiguo Feng(Stanford University)Yue Xu(Stanford University)Chuong D. Hoang(Stanford University)Maximilian Diehn(California Institute for Regenerative Medicine)Ash A. Alizadeh(Center for Systems Biology)
Gene expression and cancer classificationMolecular Biology Techniques and ApplicationsSingle-cell and spatial transcriptomicsEnumerationBiologyHaematopoiesisRNAGeneComputational biologyHematopoietic cellCellGene expressionMolecular biology
MeSH terms
Gene Expression RegulationHumansRNASoftwareTissue PreservationPalatine TonsilReproducibility of ResultsBiomarkersTissue Culture TechniquesTranscriptome
Citations
13,801
FWCI
87.67
field-weighted impact
References
35
Percentile
100%
vs. same field & year
Citations per year
Cited by
TIMER2.0 for analysis of tumor-infiltrating immune cells
Nucleic Acids Research · 2020 · 5,542 citations
Simultaneous enumeration of cancer and immune cell types from bulk tumor gene expression data
eLife · 2017 · 1,421 citations
ImmuCellAI: A Unique Method for Comprehensive T‐Cell Subsets Abundance Prediction and its Application in Cancer Immunotherapy
Advanced Science · 2020 · 1,015 citations
The prognostic landscape of tumor-infiltrating immune cell and immunomodulators in lung cancer
Biomedicine & Pharmacotherapy · 2017 · 385 citations
Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species
Immunity · 2019 · 1,454 citations
xCell: digitally portraying the tissue cellular heterogeneity landscape
Genome biology · 2017 · 4,570 citations
Identification and Verification of Immune-Related Gene Prognostic Signature Based on ssGSEA for Osteosarcoma
Frontiers in Oncology · 2020 · 339 citations
Determining cell type abundance and expression from bulk tissues with digital cytometry
Nature Biotechnology · 2019 · 4,725 citations
References
Statistical significance for genomewide studies
Proceedings of the National Academy of Sciences · 2003 · 10,009 citations
Ridge Regression: Biased Estimation for Nonorthogonal Problems
Technometrics · 2000 · 6,566 citations
Multicollinearity in Regression Analysis: The Problem Revisited
The Review of Economics and Statistics · 1967 · 1,929 citations
Hallmarks of Cancer: The Next Generation
Cell · 2011 · 65,668 citations
Inferring tumour purity and stromal and immune cell admixture from expression data
Nature Communications · 2013 · 10,540 citations
Practical selection of SVM parameters and noise estimation for SVM regression
Neural Networks · 2003 · 2,017 citations
New Support Vector Algorithms
Neural Computation · 2000 · 2,793 citations
Ridge Regression: Biased Estimation for Nonorthogonal Problems
Technometrics · 1970 · 8,581 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
