review Open AccessTop 1% cited
Advances in mRNA Vaccines for Infectious Diseases
Frontiers in Immunology · 2019 · Vol. 10 · pp. 594–594
Cuiling Zhang(Qingdao Agricultural University)Giulietta Maruggi(GlaxoSmithKline (United States))Hu Shan(Qingdao Agricultural University)Junwei Li✉(Qingdao Agricultural University)
Abstract
During the last two decades, there has been broad interest in RNA-based technologies for the development of prophylactic and therapeutic vaccines. Preclinical and clinical trials have shown that mRNA vaccines provide a safe and long-lasting immune response in animal models and humans. In this review, we summarize current research progress on mRNA vaccines, which have the potential to be quick-manufactured and to become powerful tools against infectious disease and we highlight the bright future of their design and applications.
RNA Interference and Gene DeliveryImmunotherapy and Immune ResponsesViral gastroenteritis research and epidemiologyInfectious disease (medical specialty)MedicineImmune systemClinical trialImmunologyDiseaseComputational biologyBiologyBioinformaticsPathology
MeSH terms
Communicable Disease ControlCommunicable DiseasesHumansRNA, MessengerVaccinationVaccines, Synthetic
Funding
- Qingdao Agricultural University
Citations
675
FWCI
37.43
field-weighted impact
References
172
Percentile
100%
vs. same field & year
Citations per year
Cited by
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