article Open AccessTop 1% cited
Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity
Cell stem cell · 2018 · Vol. 23(2) · pp. 181–192.e5
Ye Li(University of California, San Diego)David Hermanson(University of Minnesota)Branden S. Moriarity(University of Minnesota)Dan S. Kaufman✉(University of California, San Diego)
Immune Cell Function and InteractionCAR-T cell therapy researchT-cell and B-cell ImmunologyBiologyChimeric antigen receptorReceptorCell biologyAntigenImmunologyCancer researchImmunotherapyImmune systemGenetics
MeSH terms
Receptors, Chimeric AntigenAnimalsCells, CulturedFemaleHumansKiller Cells, NaturalOvarian NeoplasmsMice, SCIDMice, Inbred NODK562 CellsMiceInduced Pluripotent Stem CellsCell Engineering
Funding
- University of Minnesota
- Comissão Interministerial para os Recursos do Mar
- National Institutes of Health
Citations
969
FWCI
35.51
field-weighted impact
References
75
Percentile
100%
vs. same field & year
Citations per year
References
Up on the tightrope: natural killer cell activation and inhibition
Nature Immunology · 2008 · 1,637 citations
Human natural killer cells
Blood · 2008 · 1,869 citations
Activation, coactivation, and costimulation of resting human natural killer cells
Immunological Reviews · 2006 · 636 citations
Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer
Blood · 2005 · 1,884 citations
Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia
Science Translational Medicine · 2016 · 896 citations
Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells
Science Translational Medicine · 2017 · 876 citations
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