In vivo pharmacological investigations of the crude extracts of Calamus viminalis (L.)

Abstract

The present study was done to evaluate in vivo anti-pyretic, gastrointestinal motility, anti-nociceptive, neuropharmacological and acute toxicity effects of different leaf extracts of Calamus viminalis in Swiss albino mice following oral administration. In vivo gastrointestinal motility test revealed that both the doses of ethanol extracts (100 and 200 mg/kg body weight) and the dose of 200 mg/kg body weight of methanol extract showed maximum charcoal defection time, compared with the effect produced by standard drug. Both methanol 100 and 200 mg/kg and chloroform 200 mg/kg extracts showed significant in vivo anti-pyretic effect on mice. Statistically significant (p