Piperine and isoflavan-4-one from the stems of Piper chaba Hunter and their In vitro antimicrobial activities

Abstract

A known piperine (1), along with two new isoflavan-4-one (2, 3) were isolated from the ethanol extract of ethyl acetate fraction of Piper chaba H. stems. The chemical structure of these compounds were established by detailed spectral data and in comparison with their spectral data reported earlier. The study was also performed to determine the in vitro antimicrobial activity by disc diffusion method. Among them, the pure compound 1 showed good antimicrobial activity against all of the test micro-organisms, fungi and standard Kanamycin.